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GenPharmTox BioTech AG
phone: +49 (0) 89 89 55 59 - 0
eMail: info@genpharmtox.de
 
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In vitro Services

1. Absorption
1.1. Caco-2 Permeability Assay

2. Metabolic Stability
2.1. Drug Discovery Screen
2.2. Drug Development Assay

3. CYP Profiling
3.1. Human Recombinant Enzymes
3.2. Chemical Inhibition
3.3. Correaltion Analysis

4. Enzyme Kinetics

5. Species Comparison and Metabolite Profiling
5.1. Available Species, Strains and Test Systems
5.2. Study Outline

6. CYP Inhibition
6.1. Drug Discovery Screen
6.2. Determination of the IC50
6.3. Determination of the Ki

7. CYP Induction



In vivo Services

1. General Considerations
1.1. Animal Welfare
1.2. Homogeneity and Stability

2. Pharmacokinetics

GenPharmTox BioTech AG • phone: +49 (0) 89 89 55 59-0 • fax: +49 (0) 89 89 55 59-18 • eMail: info@genpharmtox.de

PDF Download
Metabolic Stability
[size 48 KB]
CYP Profiling
[size 63 KB]
Enzyme Kinetics
[size 61 KB]
Metabolite Profiling
[size 63 KB]
CYP Inhibition
[size 47 KB]
CYP Induction
[size 46 KB]
   
ADME
[size 129 KB]
Catalogue Services in ADME-Tox
[size 323 KB]

"Individual expertise in finding solutions at the preclinical stage and a high level of reliability are strengths we particularly appreciate in GenPharmTox for a partnership-based collaboration."
Dr. Michael Gassen, 4SC AG